SARS-CoV-2 and Influenza Co-Infection: Fair Competition or Sinister Combination?

SARS-CoV-2 and Influenza Co-Infection: Fair Competition or Sinister Combination?

Blog Article

The COVID-19 pandemic remains a serious public health problem globally.During winter influenza seasons, more aggressive SARS-CoV-2 infections and fatalities have been documented, indicating that influenza co-infections may significantly impact the disease outcome of COVID-19.Both influenza and SARS-CoV-2 viruses share many similarities in their transmission and their cellular tropism for replication in the human respiratory tract.However, the Clothing complex intricacies and multi-faceted dynamics of how the two pathogens interact to ensure their survival in the same lung microenvironment are still unclear.In addition, clinical studies on influenza co-infections in COVID-19 patients do not provide conclusive evidence of how influenza co-infection mechanistically modifies disease outcomes of COVID-19.

This review discusses various viral as well as host factors that potentially influence the survival or synergism of these Windshield Header two respiratory pathogens in the infected lung microenvironment.